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除癌胚抗原和甲胎蛋白外的胃肠道肿瘤标志物。

Gastrointestinal tumor markers, other than carcinoembryonic antigen, and alpha fetal protein.

作者信息

Klavins J V

出版信息

Cancer Detect Prev. 1983;6(1-2):131-6.

PMID:6883374
Abstract

Oncofetal markers for colon carcinomas are CSAp, a nonsulfated mucin, a second trimester fetal antigen, an altered thymidine kinase, a monosialoganglioside, and glycolipid antigens. For gastric carcinoma, they are basic fetoprotein, a sulfoglycoprotein, and for pancreatic carcinomas--POA, an oncofetal pancreatic antigen, and designated as CAPI, an oncofetal antigen. Tumor-associated markers for colon carcinomas are: UDP-galactosyltransferase and zinc glycinate marker; for gastric carcinomas, sulfated glycoprotein and for pancreatic carcinomas, pancreas carcinoma-associated antigen, a polycytidylic acid-specific ribonuclease, and galactosyltransferase. Suggested as tumor-specific markers for colon carcinomas are an altered mucoprotein, basic antigen, beta 2-microglobulin-associated antigen, and a specific adenosine deaminase; for gastric carcinomas, a specific protein, an antigen with 3-oxyanthranilic acid, and an antigen of unknown origin in gastric secretions; for pancreatic carcinomas, an antigen with molecular weight of 380,000 daltons and an antigen suggested by tumor immunity.

摘要

结肠癌的癌胚标志物有CSAp(一种非硫酸化粘蛋白)、一种孕中期胎儿抗原、一种改变的胸苷激酶、一种单唾液酸神经节苷脂和糖脂抗原。胃癌的癌胚标志物有碱性甲胎蛋白、一种磺基糖蛋白,而胰腺癌的癌胚标志物有POA(一种癌胚胰腺抗原)和被命名为CAPI的一种癌胚抗原。结肠癌的肿瘤相关标志物有:UDP - 半乳糖基转移酶和甘氨酸锌标志物;胃癌的有硫酸化糖蛋白,胰腺癌的有胰腺癌相关抗原、一种聚胞苷酸特异性核糖核酸酶和半乳糖基转移酶。被认为是结肠癌肿瘤特异性标志物的有改变的粘蛋白、碱性抗原、β2 - 微球蛋白相关抗原和一种特异性腺苷脱氨酶;胃癌的有特异性蛋白、一种含3 - 氧代邻氨基苯甲酸的抗原和胃分泌物中一种来源不明的抗原;胰腺癌的有分子量为380,000道尔顿的抗原和肿瘤免疫所提示的一种抗原。

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