甲状旁腺切除术对斑泥螈（Desmognathus monticola）血浆钙水平的影响。

Effect of parathyroidectomy on plasma calcium levels in the seal salamander, Desmognathus monticola.

作者信息

Wittle L W

出版信息

Gen Comp Endocrinol. 1983 Jul;51(1):159-62. doi: 10.1016/0016-6480(83)90109-0.

Abstract

The parathyroid glands of Desmognathus monticola are located in the subdermal connective tissue of the neck. Although they are smaller than previously described urodele parathyroid glands, their histological structure is similar. Parathyroidectomy caused a decrease in plasma calcium concentrations within 4 days following the operation. By Days 12 and 21, however, the plasma calcium levels of parathyroidectomized animals were not significantly different from those of sham-operated animals. Thus, the parathyroid gland of this species contains a hypercalcemic principle, but the recovery from hypocalcemia suggests that some hypercalcemic mechanism other than the parathyroid system must be involved in calcium homeostasis.

摘要

蒙特科尔纳特螈（Desmognathus monticola）的甲状旁腺位于颈部的皮下结缔组织中。尽管它们比先前描述的有尾目动物的甲状旁腺小，但它们的组织结构相似。甲状旁腺切除术后4天内，血浆钙浓度下降。然而，在第12天和第21天，甲状旁腺切除动物的血浆钙水平与假手术动物的血浆钙水平没有显著差异。因此，该物种的甲状旁腺含有一种高血钙素，但低血钙症的恢复表明，除甲状旁腺系统外，一些其他的高血钙机制一定参与了钙稳态的维持。