衰老大鼠不同脑区的钙调蛋白含量
Calmodulin content in different brain areas of aging rats.
作者信息
Teolato S, Calderini G, Bonetti A C, Toffano G
出版信息
Neurosci Lett. 1983 Jul 15;38(1):57-60. doi: 10.1016/0304-3940(83)90110-6.
An age-related decrease of calmodulin content was detected in the striatum, cerebral cortex and cerebellum of 3-, 22- and 30-month-old rats. This age-related decrease of calmodulin level occurred both in the supernatant and in the pellet fraction of high speed centrifuged tissues. However, the rates of age-dependent calmodulin loss in the pellet and supernatant fraction were differentiated according to the cerebral region considered, suggesting a different brain area sensitivity to the aging process.
在3个月、22个月和30个月大的大鼠的纹状体、大脑皮层和小脑中，检测到钙调蛋白含量随年龄增长而降低。这种钙调蛋白水平随年龄增长的降低在高速离心组织的上清液和沉淀组分中均有发生。然而，根据所考虑的脑区不同，沉淀和上清组分中钙调蛋白随年龄减少的速率也有所不同，这表明不同脑区对衰老过程的敏感性不同。
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