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感染立氏立克次体和蒙大拿立克次体的豚鼠的血清学交叉反应和交叉保护作用

Serological cross-reaction and cross-protection in guinea pigs infected with Rickettsia rickettsii and Rickettsia montana.

作者信息

Feng W C, Waner J L

出版信息

Infect Immun. 1980 May;28(2):627-9. doi: 10.1128/iai.28.2.627-629.1980.

Abstract

Antisera produced in guinea pigs inoculated with Rickettsia rickettsii or Rickettsia montana were cross-reactive but sufficiently specific to identify the primary infecting agent. Guinea pigs immunized with R. montana were protected from fatal infection with R. rickettsii, although a few (25%) developed mild fever of short duration.

摘要

用立氏立克次体或蒙大拿立克次体接种豚鼠产生的抗血清有交叉反应,但特异性足以识别主要感染病原体。用蒙大拿立克次体免疫的豚鼠可免受立氏立克次体的致命感染,不过有少数(25%)会出现持续时间较短的轻度发热。

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