Shimamoto K, Chao J, Margolius H S
Tohoku J Exp Med. 1982 Jul;137(3):269-74. doi: 10.1620/tjem.137.269.
Inactive kallikrein (prekallikrein) in human urine was discovered recently. A more accurate method to measure this zymogen and total kallikrein is described. With trypsin pretreatment, it was found that 35.3 +/- 2.7% of total urinary kallikrein activity was prekallikrein. The results are supported by a new direct radioimmunoassay which measures predominantly active kallikrein.
人尿中的无活性激肽释放酶(前激肽释放酶)最近被发现。本文描述了一种更精确的方法来测量这种酶原和总激肽释放酶。经胰蛋白酶预处理后,发现尿中总激肽释放酶活性的35.3±2.7%是前激肽释放酶。这些结果得到了一种主要测量活性激肽释放酶的新型直接放射免疫测定法的支持。