Ousterhout D K, Baker S, Zlotolow I
J Maxillofac Surg. 1980 Aug;8(3):228-33. doi: 10.1016/s0301-0503(80)80105-6.
Craniosynostosis (Cruzon's, Pfeiffer's and Apert's Syndrome, etc.) can cause forehead deformities that frequently need reconstruction. In general, osteotomies and/or bone grafting are the preferred methods for obtaining proper orbital protection from above and a good aesthetic appearance. In certain cases however, osteotomies and/or bone grafting are not possible or a patient may refuse to have such an extensive procedure. Preformed methylmethacrylate prostheses have in such cases been implanted in patients with significant skull deformities with only minimal morbidity. The ease of this technique coupled with the shortened operative time, minimal hospitalization, and few, minor complications offer the reconstructive surgeon another and relatively simple method for treatment of extensive forehead and supraorbital deformities.
颅缝早闭(克鲁宗综合征、菲佛综合征和阿佩尔综合征等)可导致前额畸形,这类畸形常常需要进行修复。一般来说,截骨术和/或骨移植是从上方获得适当眼眶保护及良好美观效果的首选方法。然而,在某些情况下,无法进行截骨术和/或骨移植,或者患者可能拒绝接受如此复杂的手术。在这种情况下,已为有严重颅骨畸形的患者植入预制的聚甲基丙烯酸甲酯假体,且发病率极低。该技术操作简便,手术时间缩短,住院时间短,并发症少且轻微,为重建外科医生提供了另一种相对简单的方法来治疗广泛性前额和眶上畸形。