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体细胞寄生与体细胞组织相容性的进化。

Somatic cell parasitism and the evolution of somatic tissue compatibility.

作者信息

Buss L W

出版信息

Proc Natl Acad Sci U S A. 1982 Sep;79(17):5337-41. doi: 10.1073/pnas.79.17.5337.

Abstract

Selection pressures proposed to account for the convergent evolution of self/not-self recognition systems in lower organisms include defense against microbial parasites and somatic cell variants. Direct support for the existence of somatic cell parasites in natural populations has been lacking. I here report the occurrence of a somatic cell parasite in the cellular slime mold Dictyostelium mucoroides and discuss the implications of this phenomenon to the evolution of mechanisms of somatic tissue compatibility.

摘要

被认为可解释低等生物中自我/非自我识别系统趋同进化的选择压力包括抵御微生物寄生虫和体细胞变异体。一直缺乏对自然种群中体细胞寄生虫存在的直接支持。我在此报告在细胞黏菌毛霉状网柄菌中出现了一种体细胞寄生虫,并讨论这一现象对体细胞组织相容性机制进化的影响。

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