Teplick S K, Pavlides C A, Goodman L R, Babayan V K
AJR Am J Roentgenol. 1982 Feb;138(2):271-3. doi: 10.2214/ajr.138.2.271.
A new gallstone solvent, monooctanoin, was tested in vitro on gallstones from 43 patients and compared with heparin, sodium dehydrocholate, and saline. Monooctanoin proved to be an excellent solvent, far superior to the other agents. It can completely dissolve or substantially reduce the size of most gallstones (except those composed of bilirubinate) in a relatively short time. Monooctanoin has been used on the bile duct stones in humans with favorable results. It can often eliminate the need for basket extraction of retained bile duct calculi. Potentially, it may be used to dissolve bile duct or gallbladder calculi in patients who are poor surgical risks.
一种新型胆石溶解剂单辛脂，在体外对43例患者的胆石进行了试验，并与肝素、去氢胆酸钠及生理盐水作了比较。结果证明单辛脂是一种极好的溶解剂，远比其他药剂优越。它能在较短时间内完全溶解或显著减小大多数胆石（除胆红素结石外）的体积。单辛脂已用于人体胆管结石，效果良好。它常常可以使保留在胆管内的结石无需用取石篮取出。在外科手术风险较大的患者中，它有可能用于溶解胆管或胆囊结石。
