Haddy T B
Am J Pediatr Hematol Oncol. 1982 Fall;4(3):285-92.
A review of the literature indicates that black children in the United States have a lower overall incidence of cancer and are less prone to leukemia and certain solid tumors, including neuroblastoma, rhabdomyosarcoma, Ewing's sarcoma, testicular tumors, liver tumors, and malignant melanoma, than are white children. Black children with acute lymphoblastic leukemia and retinoblastoma, but not with neuroblastoma, Wilms' tumor, and rhabdomyosarcoma, have poorer survival rates than white children. Socioeconomic status appears to be an important reason for the discrepant outlook, but genetic differences may also play a role. Consideration of these issues will assist in planning appropriate treatment regimens.
文献综述表明,美国黑人儿童的总体癌症发病率较低,与白人儿童相比,患白血病和某些实体瘤(包括神经母细胞瘤、横纹肌肉瘤、尤因肉瘤、睾丸肿瘤、肝肿瘤和恶性黑色素瘤)的倾向较小。患有急性淋巴细胞白血病和视网膜母细胞瘤的黑人儿童,而非患有神经母细胞瘤、肾母细胞瘤和横纹肌肉瘤的黑人儿童,其生存率低于白人儿童。社会经济地位似乎是导致这种差异的一个重要原因,但基因差异也可能起作用。对这些问题的考虑将有助于制定适当的治疗方案。