蛋白AA与格子状角膜营养不良。

Protein AA and lattice corneal dystrophy.

作者信息

Mondino B J, Raj C V, Skinner M, Cohen A S, Brown S I

出版信息

Am J Ophthalmol. 1980 Mar;89(3):377-80. doi: 10.1016/0002-9394(80)90007-0.

Abstract

A 73-year-old woman underwent corneal transplantation because of lattice dystrophy. Histopathologic examination of the excised host cornea disclosed eosinophilic deposits that stained positively with Congo red and showed green birefringence with polarized light. Immunofluorescent examination showed protein AA and protein AP in the stromal deposits. To the best of our knowledge, this is the first report of protein AA and protein AP in the amyloid deposits of lattice corneal dystrophy.

摘要

一名73岁女性因格子状角膜营养不良接受了角膜移植。对切除的宿主角膜进行组织病理学检查发现嗜酸性沉积物，其刚果红染色呈阳性，偏振光下显示绿色双折射。免疫荧光检查显示基质沉积物中有AA蛋白和AP蛋白。据我们所知，这是关于格子状角膜营养不良淀粉样沉积物中AA蛋白和AP蛋白的首次报道。