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[粘质沙雷氏菌引起的医院感染及其对抗生素的敏感性]

[Hospital infection due to Serratia marcescens and its sensitivity to antibiotics].

作者信息

Filloy L, Serrano D, Borjas E

出版信息

Bol Med Hosp Infant Mex. 1980 Sep-Oct;37(5):871-7.

PMID:7000092
Abstract

A total of 164 isolations of Serratia marcescens achieved during 1978-1979 at the Hospital Infantil de México in children with various pathology due to this bacteria were studied. Most of the cases were debilitated patients from the newborns and prematures wards and contagious and surgery departments. The most frequent isolations were from wounds and abscesses (76 cases), the same as from meningitis (22 cases) and sepsis (12 patients). Serratia marcescens showed a high degree of resistance (87-100%) to the following antibiotics: carbenicillin, colimycin, chloramphenicol, phosphomicin, ampicillin and cephalothin. To gestamicin and kanamycin, 42% of strains were sensitive. Amikacin was the most effective drug with 92% of strains susceptible to it. The history of this bacteria, its mode of transmission, frequency of infections and resistance to antibiotics found in foreign institutions are commented. Likewise, the difficulty for the precision bacteriologic diagnosis is emphasized as the possible main cause for the ignorance in Mexico of infections due to this bacteria.

摘要

对1978年至1979年期间在墨西哥儿童医院从患有各种由粘质沙雷氏菌引起病变的儿童身上获取的164株粘质沙雷氏菌分离株进行了研究。大多数病例是来自新生儿和早产儿病房以及传染病科和外科的体弱患者。最常见的分离株来自伤口和脓肿(76例),与脑膜炎(22例)和败血症(12例患者)中的情况相同。粘质沙雷氏菌对以下抗生素表现出高度耐药性(87%-100%):羧苄青霉素、粘菌素、氯霉素、磷霉素、氨苄青霉素和头孢噻吩。对于庆大霉素和卡那霉素,42%的菌株敏感。阿米卡星是最有效的药物,92%的菌株对其敏感。文中对这种细菌的历史、传播方式、感染频率以及在国外机构中发现的对抗生素的耐药性进行了评论。同样,强调了精确细菌学诊断的困难,这可能是墨西哥对这种细菌引起的感染认识不足的主要原因。

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