多潘立酮作为抗肿瘤化疗中的止吐药
[Domperidone as an anti-emetic in antineoplastic chemotherapy].
作者信息
Caruso U, D'Iddio S, Cravotto E, Pesce S, Betti I, Ruscitto G, Ecari U, Sabrie A M
出版信息
Minerva Chir. 1981 Jun 15;36(11):787-91.
PMID:7019761
Abstract
The antiemetic effects of domperidone in patients undergoing post-surgical cytostatic treatment for stomach and colorectal carcinoma have been evaluated. The study has been performed on 3 groups of patients treated with domperidone, metoclopramide and placebo respectively. The antiemetic activity of domperidone proved to be better than that of metoclopramide. No side effects were observed in patients treated with domperidone.
摘要
已对多潘立酮在接受胃癌和结直肠癌术后细胞抑制治疗患者中的止吐效果进行了评估。该研究针对分别接受多潘立酮、甲氧氯普胺和安慰剂治疗的三组患者开展。结果证明，多潘立酮的止吐活性优于甲氧氯普胺。接受多潘立酮治疗的患者未观察到副作用。
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