Bull World Health Organ. 1981;59(1):1-8.
This report summarizes the available information on the immunology of filariasis, and discusses immunodiagnosis and the immunological factors influencing the host-parasite relationship in lymphatic filariasis and onchocerciasis. Several areas that require further research are identified, particularly concerning the development of new serological techniques, and the fractionation of specific antigens. The problems associated with vaccine development are considered and the importance of finding better animal models for research is stressed.
本报告总结了关于丝虫病免疫学的现有信息,并讨论了免疫诊断以及影响淋巴丝虫病和盘尾丝虫病宿主-寄生虫关系的免疫因素。确定了几个需要进一步研究的领域,特别是关于新血清学技术的开发以及特定抗原的分离。考虑了与疫苗开发相关的问题,并强调了寻找更好的动物研究模型的重要性。