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通过局部立体定向射频损伤在猫身上产生的去大脑强直。

Decerebrate rigidity produced in cats by focal stereotactic radiofrequency lesions.

作者信息

Tsementzis S A, Gillingham F J, Gordon A, Hitchcock E R, Campbell D, Mendelow A D

出版信息

Acta Neurochir (Wien). 1981;59(1-2):13-33. doi: 10.1007/BF01411188.

Abstract

A method of producing decerebrate rigidity in cats by means of a radio frequency current was developed. Adequate control of the extent an shape of the lesions necessitated a preliminary investigation of the relationship between the intensity and duration of current, the size of the lesion, and the tissue impedance before and after destruction; this was performed on guinea pigs. The mesencephalic reticulum in cats was identified by depth microelectrode recording and electrical stimulation. Unilateral, midline, and combined stereotactic radiofrequency lesions were made. The anatomical location, the pathological characteristics, and the physiological significance of the lesions with regard to the production of decerebrate rigidity and of the other clinical reactions of the animals are discussed.

摘要

开发了一种通过射频电流在猫身上产生去大脑僵直的方法。要对病变的范围和形状进行充分控制,就需要预先研究电流强度与持续时间、病变大小以及破坏前后组织阻抗之间的关系;这是在豚鼠身上进行的。通过深度微电极记录和电刺激来识别猫的中脑网状结构。制作了单侧、中线和联合立体定向射频损伤。讨论了这些损伤在产生去大脑僵直及动物其他临床反应方面的解剖位置、病理特征和生理意义。

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