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用噬菌体对大肠杆菌粗糙菌株进行分型(作者译)

[Typing of E. coli rough strains with phages (author's transl)].

作者信息

Nimmich W, Straube E, Naumann G

出版信息

Zentralbl Bakteriol Mikrobiol Hyg A Med Mikrobiol Infekt Parasitol. 1981 Dec;251(1):33-9.

PMID:7036596
Abstract

Two phage-sets were used for the typing of 408 E. coli rough strains isolated from patients with urinary tract infections, Using the 13 phages A to M (11), we were able to type 225 (55.1 per cent) strains. 143 (35 per cent) of these strains were found to have K antigen, 84 different phage patterns could be recognized. Phage patterns GHK, M, F, and AM were the most common ones found. The application of the typical rough phages Br10, C21, 6SR, FP1, T4, and the Felix O (FO) phage led to the successful typing of 143 (35 per cent) strains, 80 of which (19.6 per cent) had a K antigen. About 70 per cent of the strains typable were found to belong to phage patterns which were represented by single phages, 24 different R phage patterns were observed. Considering both phage-sets the total typability amounted to 67 per cent. It is concluded that phage typing may be useful for the typing of E. coli rough strains in urinary tract infections in order to distinguish between relapse and reinfection.

摘要

使用两组噬菌体对从尿路感染患者中分离出的408株大肠杆菌粗糙型菌株进行分型。使用13种从A到M的噬菌体(11),我们能够对225株(55.1%)菌株进行分型。其中143株(35%)菌株被发现有K抗原,可识别出84种不同的噬菌体型。噬菌体型GHK、M、F和AM是最常见的。应用典型的粗糙型噬菌体Br10、C21、6SR、FP1、T4和费利克斯O(FO)噬菌体成功地对143株(35%)菌株进行了分型,其中80株(19.6%)有K抗原。发现约70%可分型的菌株属于由单个噬菌体代表的噬菌体型,观察到24种不同的R噬菌体型。综合考虑两组噬菌体,总分型率为67%。得出的结论是,噬菌体分型可能有助于对尿路感染中的大肠杆菌粗糙型菌株进行分型,以便区分复发和再感染。

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