传染性牛角膜结膜炎实验动物模型的建立。
Development of a laboratory animal model for infectious bovine keratoconjunctivitis.
作者信息
Chandler R L, Turfrey B A, Smith K
出版信息
Res Vet Sci. 1982 Jan;32(1):128-30.
PMID:7045996
Abstract
Guinea pigs, gerbils, voles, golden hamsters and Chinese hamsters exposed to experimental infection with Moraxella bovis by ocular instillation or associated routes showed transient infections only and no clinical signs. Five strains of mice were of similarly low susceptibility but another, the C57 Bl strain, was relatively susceptible and treatment with corticosteroid before infection regularly produced keratoconjunctivitis. This system therefore offers a promising model for studies on infectious bovine keratoconjunctivitis.
摘要
通过眼内滴注或相关途径接受牛莫拉菌实验性感染的豚鼠、沙鼠、田鼠、金黄仓鼠和中国仓鼠仅表现出短暂感染，且无临床症状。五株小鼠的易感性同样较低，但另一株C57 Bl小鼠相对易感，感染前用皮质类固醇治疗通常会引发角膜结膜炎。因此，该系统为传染性牛角膜结膜炎的研究提供了一个有前景的模型。
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Development of a laboratory animal model for infectious bovine keratoconjunctivitis.传染性牛角膜结膜炎实验动物模型的建立。
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引用本文的文献
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A 2-year randomized blinded controlled trial of a conditionally licensed Moraxella bovoculi vaccine to aid in prevention of infectious bovine keratoconjunctivitis in Angus beef calves.一项为期 2 年的、条件许可的牛巴氏杆菌疫苗随机盲法对照临床试验，旨在帮助预防安格斯肉牛犊传染性牛角膜结膜炎。
J Vet Intern Med. 2019 Nov;33(6):2786-2793. doi: 10.1111/jvim.15633. Epub 2019 Oct 12.
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