Kondo M, Ando N, Kosuda S, Lian S, Kubo A, Masaki H, Hashimoto S, Tsutsui T, Kakegawa T
Cancer. 1982 Mar 1;49(5):1031-4. doi: 10.1002/1097-0142(19820301)49:5<1031::aid-cncr2820490529>3.0.co;2-o.
The authors evaluated Ga-67 scan in 68 patients with intrathoracic esophageal carcinoma initially planned for surgery. Of these, 59 patients were staged pathologically or surgically; their Ga-67 scan results correctly predicted the presence of extraesophageal spread and lymph node metastases. Of 38 clinical Stage II patients, 15 (39%) could be Stage III by the results of Ga-67 scan. However, two of four clinical Stage I patients (50%) and 35 of 38 clinical Stage II patients (92%) were eventually pathologic or surgical Stage III. This high conversion rate and the high incidence of Stage III in esophageal carcinoma patients may not justify routine use of Ga-67 scan only for staging. Ga-67 scan, however, was useful for planning radiotherapy, because missing extraesophageal extension or gross metastases from the radiation fields were detected in six patients of 51 so treated. Ga-67 scan has its value in some patients with intrathoracic esophageal carcinoma.
作者对68例最初计划接受手术的胸段食管癌患者进行了镓-67扫描。其中,59例患者进行了病理分期或手术分期;他们的镓-67扫描结果正确预测了食管外扩散和淋巴结转移的存在。在38例临床II期患者中,15例(39%)根据镓-67扫描结果可能为III期。然而,4例临床I期患者中有2例(50%)以及38例临床II期患者中有35例(92%)最终病理分期或手术分期为III期。这种高转化率以及食管癌患者中III期的高发生率可能说明仅将镓-67扫描用于分期并无常规使用的必要。然而,镓-67扫描对放疗计划很有用,因为在接受治疗的51例患者中有6例检测到放射野遗漏了食管外扩展或大体转移灶。镓-67扫描在一些胸段食管癌患者中具有价值。