Revesz G, Shea F J, Kundel H L
Radiology. 1982 Mar;142(3):615-8. doi: 10.1148/radiology.142.3.7063674.
Chest examinations, consisting of three posteroanterior chest radiographs obtained at 75,120, and 140 kVp, were performed on patients with clinically suspected pulmonary disease. The 66 sets of radiographs included 23 lung cancers, 13 other clinically relevant abnormalities, and 27 normals. All findings were verified by clinical or radiologic follow-up except for three cases that could not be verified and were excluded from later analysis. Six radiologists viewed the series of 198 radiographs one at a time in a randomized sequence. They scored each radiograph and each suspected abnormality with a confidence rating from 1 (normal) to 4 (definitely abnormal). Based on these scores receiver operating characteristic (ROC) curves were plotted for each set of kVp settings. The results indicated that higher kVp values improved diagnostic accuracy. Analysis of the ROC curves showed statistically significant differences between 140 kVp and both 120 kVp and 75 kVp, but not between the two lower kVp values.
对临床疑似肺部疾病的患者进行胸部检查，包括在75、120和140 kVp下拍摄三张后前位胸片。这66组X光片包括23例肺癌、13例其他临床相关异常以及27例正常情况。除3例无法核实的病例被排除在后续分析之外，所有检查结果均通过临床或影像学随访得到证实。六位放射科医生以随机顺序逐一查看这198张X光片。他们对每张X光片和每个疑似异常情况进行评分，置信度从1（正常）到4（肯定异常）。根据这些评分，针对每组千伏设置绘制了受试者操作特征（ROC）曲线。结果表明，较高的千伏值提高了诊断准确性。ROC曲线分析显示，140 kVp与120 kVp和75 kVp之间存在统计学显著差异，但两个较低千伏值之间没有差异。
