Kinetics of the spread of the Yoshida ascites hepatoma cancer cells through various organs of the rat.

In the present paper the attempt is pursued to provide a self-consistent interpretation for the quantitative measurements of the amount of neoplastic cells found at different anatomic sites and at various times after intraperitoneal injection. The model, employing a system of 8 linear differential equations with constant coefficients, can be fitted by means of a special program for a small processing system equipped with an 8-bit microprocessor and 48 KB of central memory.