Healton E B, Zito G, Chauhan P, Brust J C
J Neurosurg. 1982 May;56(5):728-31. doi: 10.3171/jns.1982.56.5.0728.
A patient is reported in whom a subdural sarcoid granuloma caused symptoms of an intracranial mass lesion, and disappeared following steroid therapy. Twenty-three previous cases with large intracranial sarcoid granulomas have been documented, a review of these 24 cases leads the authors to conclude that: 1) neither symptoms nor nonhistological diagnostic studies, including computerized tomography, differentiate sarcoid from cerebral neoplasms or other central nervous granulomas; and 2) because sarcoid mass lesions frequently respond well to corticosteroid therapy, surgery should probably be reserved for cases in which there is diagnostic uncertainty, a need for emergency decompression, or lack of response to steroids.
据报道，一名患者患有硬膜下结节病肉芽肿，出现颅内占位性病变症状，经类固醇治疗后消失。此前已有23例颅内巨大结节病肉芽肿的病例记录，对这24例病例的回顾使作者得出以下结论：1）症状和包括计算机断层扫描在内的非组织学诊断研究均无法区分结节病与脑肿瘤或其他中枢神经系统肉芽肿；2）由于结节病占位性病变对皮质类固醇治疗通常反应良好，手术可能应仅用于诊断不确定、需要紧急减压或对类固醇无反应的病例。
