Lipman B, Serwer G A, Brazy J E
Pediatrics. 1982 Jun;69(6):778-81.
Blood flow patterns in the anterior cerebral arteries were studied in eight preterm infants with patent ductus arteriosus and left-to-right shunts. A noninvasive Doppler technique was used to obtain the blood flow patterns and to calculate a pulsatility index. Advancing diastolic blood flow was decreased in all eight infants, and two demonstrated retrograde anterior cerebral artery flow during diastole. Following ductal closure, the diastolic flow in the anterior cerebral arteries increased significantly, reaching levels seen in normal infants. These observations demonstrate that infants with patent ductus arteriosus and left-to-right shunts may have abnormal cerebral hemodynamics which return to normal following ductal closure.
对8例患有动脉导管未闭且有左向右分流的早产儿的大脑前动脉血流模式进行了研究。采用无创多普勒技术获取血流模式并计算搏动指数。所有8例婴儿的舒张期血流均减少，2例在舒张期出现大脑前动脉逆行血流。动脉导管闭合后，大脑前动脉的舒张期血流显著增加，达到正常婴儿的水平。这些观察结果表明，患有动脉导管未闭且有左向右分流的婴儿可能存在异常的脑血流动力学，在动脉导管闭合后恢复正常。
