大鼠Y迷宫记忆保持能力的差异：根据旷场活动进行选择。

Differences in Y-maze retention of rats: selection according to open field activity.

作者信息

Wetzel W, Matthies H

出版信息

Physiol Behav. 1982 Apr;28(4):619-22. doi: 10.1016/0031-9384(82)90040-3.

Abstract

Adult male Wistar rats of a heterogeneous outbred population were selected according to their open field ambulation and classified into two groups: animals showing the most activity during the first 2 min (A, fast habituation), or after the first 2 min (B, delayed habituation) of a 10 min observation period. One week later these rats were tested for foot-shock motivated brightness discrimination learning and retention in a Y-maze. It was found that group A rats exhibited higher %-savings than group B rats, whereas their learning performance was not different. Thus, our results show that rats differing in their Y-maze retention ability can be selected on the basis of certain open field measures.

摘要

根据旷场活动情况，从非近亲繁殖的成年雄性Wistar大鼠群体中进行挑选，并将其分为两组：在10分钟观察期的前2分钟内表现出最高活动量的动物（A组，快速习惯化），或在最初2分钟后表现出最高活动量的动物（B组，延迟习惯化）。一周后，对这些大鼠进行足部电击激发的亮度辨别学习测试，并在Y迷宫中进行记忆保持测试。结果发现，A组大鼠的节省百分比高于B组大鼠，而它们的学习表现并无差异。因此，我们的结果表明，可以根据某些旷场测量指标来挑选在Y迷宫记忆保持能力上存在差异的大鼠。