Brenner M H, Mooney A
Soc Sci Med. 1982;16(4):431-42. doi: 10.1016/0277-9536(82)90051-x.
Analyses directed toward recent declines in cardiovascular disease mortality rates have typically focused on alterations in important physiological and behavioral risk factors resulting from lifestyle changes and medical advances. In this study, a multivariate model of the impact of more fundamental changes in the socioeconomic and bio-physical environments has been developed and applied to cardiovascular disease mortality rates, by sex, in England and Wales and Scotland during 1955-1976. The predictive model includes factors associated with (1) long-term growth in the economy, (2) deleterious behavioral risk factors loosely associated with economic growth--especially cigarette consumption per capita, (3) economic instability--especially recession as indicated by factors related to unemployment, income loss, and recessional declines in average weekly hours worked in manufacturing industries, (4) health care, and (5) physical environmental disturbances--especially very cold temperatures. This model proves to be an excellent instrument for the statistical explanation of trends and fluctuations in CVD mortality rates for both sexes and both regions in Britain in the post-War period. In general, the overall exponential rate of economic growth is found to be the most powerful factor in the long-term decline in CVD mortality rates. Similarly, disturbances to the national and regional economic situations--especially recessions--have regularly been associated with elevated death rates for all populations observed. Cigarette and unusually high spirits consumption, as well as particularly cold winter temperatures, have also had important deleterious effects on CVD mortality. The proportion of government expenditures devoted to health care is associated with a reduction in CVD mortality in England and Wales.
针对近期心血管疾病死亡率下降的分析通常集中在生活方式改变和医学进步所导致的重要生理和行为风险因素的变化上。在本研究中,我们构建了一个多变量模型,用于分析社会经济和生物物理环境中更根本变化的影响,并将其应用于1955 - 1976年期间英格兰、威尔士和苏格兰按性别划分的心血管疾病死亡率。该预测模型包括与以下因素相关的因素:(1) 经济的长期增长;(2) 与经济增长松散相关的有害行为风险因素——特别是人均香烟消费量;(3) 经济不稳定——特别是由与失业、收入损失以及制造业平均每周工作小时数的衰退性下降相关的因素所表明的衰退;(4) 医疗保健;(5) 物理环境干扰——特别是极寒温度。事实证明,该模型是对战后英国两个地区男女心血管疾病死亡率趋势和波动进行统计解释的极佳工具。总体而言,经济增长的总体指数率被发现是心血管疾病死亡率长期下降的最有力因素。同样,国家和地区经济形势的干扰——特别是衰退——一直与所有观察到的人群死亡率上升相关。香烟和烈酒的异常高消费,以及特别寒冷的冬季温度,也对心血管疾病死亡率产生了重要的有害影响。在英格兰和威尔士,政府用于医疗保健的支出比例与心血管疾病死亡率的降低相关。