Cabin H S, Roberts W C
Circulation. 1982 Jul;66(1):93-9. doi: 10.1161/01.cir.66.1.93.
The amount of cross-sectional area narrowing by atherosclerotic plaque in each 5-mm-long segment from the entire lengths of the right, left main, left anterior descending and left circumflex coronary arteries and the size, predominant location and extent of myocardial scarring were determined in 59 necropsy patients with a healed transmural myocardial infarct (MI). The mean number of the four major epicardial coronary arteries narrowed severely (76-100% in cross-sectional area) was 3.0 in the 37 patients with posterior MI and 2.6 in the 22 patients with anterior MI (p less than .025). The mean percent of severely narrowed 5-mm segments from all four major coronary arteries was similar in the anterior and posterior MI groups, 38% vs 46%. The patients with anterior MI, however, had a higher percentage of severely narrowed 5-mm segments of the left anterior descending than of the left circumflex but not the right coronary artery, 46% vs 25% (p less than 0.001) and 40% (NS). The patients with posterior MI had a higher percentage of severely narrowed segments of the right and left circumflex coronary arteries than of the left anterior descending artery, 55% and 51% vs 32% (p less than 0.05). The anterior MI group had, on the average, larger left ventricular scars than the posterior MI group (20% vs 9%, p greater than 0.002) and more frequent scarring of the ventricular septum, 16 patients (73%) vs six patients (16%) (p less than 0.001).
在59例有陈旧性透壁心肌梗死（MI）的尸检患者中，测定了右冠状动脉、左主干、左前降支和左旋支冠状动脉全长上每5毫米长节段内动脉粥样硬化斑块导致的横截面积狭窄程度，以及心肌瘢痕的大小、主要位置和范围。37例下壁心肌梗死患者中，四条主要心外膜冠状动脉严重狭窄（横截面积狭窄76%-100%）的平均数量为3.0条，22例前壁心肌梗死患者中为2.6条（p<0.025）。前壁和下壁心肌梗死组中，四条主要冠状动脉严重狭窄的5毫米节段的平均百分比相似，分别为38%和46%。然而，前壁心肌梗死患者中，左前降支严重狭窄的5毫米节段百分比高于左旋支，但右冠状动脉并非如此，分别为46%和25%（p<0.001）和40%（无显著差异）。下壁心肌梗死患者中，右冠状动脉和左旋支严重狭窄节段的百分比高于左前降支，分别为55%、51%和32%（p<0.05）。前壁心肌梗死组平均左心室瘢痕大于下壁心肌梗死组（20%对9%，p>0.002），室间隔瘢痕更常见，分别为16例（73%）和6例（16%）（p<0.001）。
