Seifert B, Hassler M P, Bettzieche H
Zentralbl Gynakol. 1982;104(1):39-44.
PGE2 and PGF2 alpha were isolated from the decidua of an early pregnancy, following medical termination. The biosynthetic capacity for 6-keto-F1 alpha was tested by incubation, using 3H-labelled arachidonic acid. Prostaglandin concentrations in the decidua differed strongly from steroid hormones in plasma. Steroid hormone concentrations increased with continuity, whereas prostaglandin values remained extremely low.
在药物流产后的早期妊娠蜕膜中分离出前列腺素E2(PGE2)和前列腺素F2α(PGF2α)。使用3H标记的花生四烯酸通过孵育来测试6-酮-前列环素F1α(6-keto-F1α)的生物合成能力。蜕膜中的前列腺素浓度与血浆中的甾体激素有很大差异。甾体激素浓度持续升高,而前列腺素值则一直极低。