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Some new evidence on human joint lubrication.关于人体关节润滑的一些新证据。
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本文引用的文献

1
ANTI-TRYPTIC ACTIVITY OF SYNOVIAL FLUID IN PATIENTS WITH VARIOUS TYPES OF ARTHRITIS.不同类型关节炎患者滑液的抗胰蛋白酶活性
J Clin Invest. 1935 Jan;14(1):124-30. doi: 10.1172/JCI100647.
2
Lubrication of animal joints. 3. The effect of certain chemical alterations of the cartilage and lubricant.动物关节的润滑。3. 软骨和润滑剂某些化学变化的影响。
Arthritis Rheum. 1968 Oct;11(5):674-82. doi: 10.1002/art.1780110510.
3
Role of hyaluronic acid in joint lubrication.透明质酸在关节润滑中的作用。
Ann Rheum Dis. 1974 Jul;33(4):318-26. doi: 10.1136/ard.33.4.318.
4
The effects of lubrication in hip joint prostheses.髋关节假体中润滑的作用。
Phys Med Biol. 1978 Mar;23(2):253-68. doi: 10.1088/0031-9155/23/2/004.

人类髋关节的润滑模式。

Modes of lubrication in human hip joints.

作者信息

Roberts B J, Unsworth A, Mian N

出版信息

Ann Rheum Dis. 1982 Jun;41(3):217-24. doi: 10.1136/ard.41.3.217.

DOI:10.1136/ard.41.3.217
PMID:7092334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1000914/
Abstract

Cadaveric hip joints were tested in a hip function simulator which subjected the femoral head to a cycle of loading and oscillation similar to that experienced during walking and measured the frictional torque transmitted to the acetabulum. Silicone fluids with viscosities from 10-2 Pa s (pascal second) to 30 Pa s were used as lubricants and the transition from mixed to full fluid film lubrication was observed around 5 x 10(-2) Pa s. Sodium carboxymethylcellulose solutions were also tested at the lower viscosities. Hyaluronidase digestion of samples of synovial fluid caused a significant increase in friction over the control samples. Trypsin digestion had no significant effect. No correlation between compliance of the cartilage and the frictional values was observed.

摘要

在髋关节功能模拟器中对尸体髋关节进行测试,该模拟器使股骨头承受类似于行走时所经历的加载和振荡循环,并测量传递至髋臼的摩擦扭矩。使用粘度范围从10⁻²帕斯卡秒(Pa s)至30 Pa s的硅油作为润滑剂,观察到在约5×10⁻² Pa s时从混合润滑转变为全液膜润滑。还在较低粘度下测试了羧甲基纤维素钠溶液。对滑液样本进行透明质酸酶消化导致摩擦力比对照样本显著增加。胰蛋白酶消化没有显著影响。未观察到软骨顺应性与摩擦值之间的相关性。