Clavert J M, Brun B, Clavert A, Buck P
Chir Pediatr. 1978;19(3):205-7.
By injections of cyclophosphamid to pregnant rabbits, we obtained different sorts of agenesis. These anomalies are the consequence of a lack of the quantity of mesenchyme necessary to the formation of the limbs. The final malformation depends on the date, the dose and the period of action of the cyclophosphamid.
通过向怀孕兔子注射环磷酰胺,我们获得了不同类型的发育不全。这些异常是肢体形成所需间充质数量不足的结果。最终的畸形取决于环磷酰胺的作用日期、剂量和作用时期。