旋毛虫感染组与未感染组大鼠膈肌中的牛磺酸水平。

Taurine levels in Trichinella spiralis infected versus noninfected rat diaphragms.

Harley J P, Clinton R T

Comp Biochem Physiol B. 1982;72(1):87-92. doi: 10.1016/0305-0491(82)90014-1.

Abstract

Trichinella spiralis muscle larvae caused a significant (P less than 0.05) reduction in the concentration of muscle taurine on day 10 and a highly significant (P less than 0.001) reduction on day 15 postinfection in rat diaphragms. 2. No significant (P greater than 0.05) taurine alteration was observed on days 5, 8, 30 and 60 post-infection. 3. Although taurine was found to be a constitutent of the amino acid pool of T. spiralis excysted larvae, its concentration was sufficiently low so as not to be a factor in adding to the taurine level of the host. 4. Carbon-14 labelled taurine was determined to be transported into T. spiralis excysted larvae. 5. The taurine pool in these larvae is probably derived from the host.

摘要

旋毛虫肌幼虫感染大鼠膈肌后第10天，肌肉中牛磺酸浓度显著降低（P<0.05），感染后第15天高度显著降低（P<0.001）。2. 感染后第5、8、30和60天未观察到牛磺酸有显著变化（P>0.05）。3. 虽然发现牛磺酸是旋毛虫脱囊幼虫氨基酸池的组成成分，但其浓度足够低，不会成为增加宿主牛磺酸水平的一个因素。4. 已确定碳-14标记的牛磺酸可转运至旋毛虫脱囊幼虫。5. 这些幼虫中的牛磺酸池可能来源于宿主。