Rossi A
Radiol Med. 1982 Apr;68(4):231-40.
The hepatic artery occlusion is compensated for the opening of pre-existing arterial anastomosis which divert the blood in to arteries downstream of the stenosis for the increase of the flow and for the portal oxygenation. The entity and the type of the collateral circulation depend on the site on the extent on the entity on the rapidity of the development and eventually on the patency of the main pre-existing anastomotic arteries. This circulation is more effective of the stenosis is in the common hepatic artery whereas it becomes more and more uneffective when the occlusion concerns the peripheral arterial branches. The increase of the portal flow occurs mainly through the splenic circulation or with the celiac trunk stenosis and in the splenectomised patients or through the mesenteric circulation thanks to a neuro-humoral mechanism which causes the opening of the precapillary arteriovenous communications. The increase of the portal flow is in correlation with the hypoxia of the hepatocyte for the decreased sinusoidal arterial supply.
肝动脉闭塞可通过先前存在的动脉吻合支开放得到代偿,这些吻合支将血液分流至狭窄下游的动脉,以增加血流量并实现门静脉氧合。侧支循环的情况和类型取决于其部位、范围、形成速度,最终还取决于主要的先前存在的吻合动脉的通畅情况。当狭窄位于肝总动脉时,这种循环更为有效,而当闭塞涉及外周动脉分支时,其有效性则越来越低。门静脉血流增加主要通过脾循环发生,或在脾切除患者中因腹腔干狭窄通过肠系膜循环发生,这是由于一种神经体液机制导致毛细血管前动静脉交通开放。门静脉血流增加与肝细胞缺氧相关,因为肝窦动脉供血减少。