Involvement of FAD-containing monooxygenase in cocaine-induced hepatotoxicity.

Suppr

超能文献

作者信息

Kloss M W, Cavagnaro J, Rosen G M, Rauckman E J

出版信息

Toxicol Appl Pharmacol. 1982 Jun 15;64(1):88-93. doi: 10.1016/0041-008x(82)90325-8.

DOI:10.1016/0041-008x(82)90325-8

PMID:7112588

Abstract

摘要

相似文献

Involvement of FAD-containing monooxygenase in cocaine-induced hepatotoxicity.

Toxicol Appl Pharmacol. 1982 Jun 15;64(1):88-93. doi: 10.1016/0041-008x(82)90325-8.

Cytochrome P-450 and FAD-monooxygenase mediated S- and N-oxygenations.细胞色素P-450和黄素腺嘌呤二核苷酸单加氧酶介导的S-和N-氧化反应。

Drug Metabol Drug Interact. 1988;6(3-4):235-44. doi: 10.1515/dmdi.1988.6.3-4.235.

Cocaine-induced hepatotoxicity in mice.可卡因诱导的小鼠肝毒性。

Toxicol Appl Pharmacol. 1978 Sep;45(3):739-54. doi: 10.1016/0041-008x(78)90167-9.

N-demethylation of cocaine to norcocaine. Evidence for participation by cytochrome P-450 and FAD-containing monooxygenase.可卡因N-去甲基化生成去甲可卡因。细胞色素P-450和含黄素腺嘌呤二核苷酸单加氧酶参与其中的证据。

Mol Pharmacol. 1983 Mar;23(2):482-5.

Effect of inhibitors of the FAD-containing monooxygenase system from rat liver microsomes on monomethylhydrazine metabolism and activation to reactive metabolites.

Arch Toxicol. 1986 May;59(1):64-6. doi: 10.1007/BF00263961.

Stereospecificity in the oxidation of phorate and phorate sulphoxide by purified FAD-containing mono-oxygenase and cytochrome P-450 isozymes.

Xenobiotica. 1988 Jan;18(1):29-39. doi: 10.3109/00498258809055134.

Cocaine-induced hepatotoxicity: lipid peroxidation as a possible mechanism.可卡因诱导的肝毒性：脂质过氧化作为一种可能的机制。

Drug Chem Toxicol. 1984;7(4):383-96. doi: 10.3109/01480548408998265.

Sulphoxidation of albendazole by the FAD-containing and cytochrome P-450 dependent mono-oxygenases from pig liver microsomes.

Xenobiotica. 1987 Oct;17(10):1159-68. doi: 10.3109/00498258709167408.

The flavoprotein domain of P450BM-3: expression, purification, and properties of the flavin adenine dinucleotide- and flavin mononucleotide-binding subdomains.P450BM-3的黄素蛋白结构域：黄素腺嘌呤二核苷酸和黄素单核苷酸结合亚结构域的表达、纯化及特性

Biochemistry. 1996 Jun 11;35(23):7528-35. doi: 10.1021/bi960330p.

Acute cocaine-induced hepatotoxicity in DBA/2Ha male mice.

Toxicol Appl Pharmacol. 1982 Aug;65(1):75-83. doi: 10.1016/0041-008x(82)90364-7.

引用本文的文献

Could Alcohol Abuse and Dependence on Junk Foods Inducing Obesity and/or Illicit Drug Use Represent Danger to Liver in Young People with Altered Psychological/Relational Spheres or Emotional Problems?酒精滥用和垃圾食品成瘾是否会导致肥胖和/或非法药物使用，从而对年轻人的心理/人际关系领域或情绪问题造成危险？

Int J Mol Sci. 2022 Sep 8;23(18):10406. doi: 10.3390/ijms231810406.

Characterization of differential cocaine metabolism in mouse and rat through metabolomics-guided metabolite profiling.通过代谢组学指导的代谢产物分析鉴定小鼠和大鼠中可卡因代谢的差异。

Drug Metab Dispos. 2013 Jan;41(1):79-88. doi: 10.1124/dmd.112.048678. Epub 2012 Oct 3.

Biotransformation of norcocaine to norcocaine nitroxide by rat brain microsomes.大鼠脑微粒体将去甲可卡因转化为去甲可卡因氮氧化物。

Psychopharmacology (Berl). 1984;84(2):221-4. doi: 10.1007/BF00427449.

Biomechanisms of cocaine-induced hepatocyte injury mediated by the formation of reactive metabolites.

Arch Toxicol. 1991;65(5):351-60. doi: 10.1007/BF02284256.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验