• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

来自耳蜗外毛细胞的细胞内记录。

Intracellular recordings from cochlear outer hair cells.

作者信息

Dallos P, Santos-Sacchi J, Flock A

出版信息

Science. 1982 Nov 5;218(4572):582-4. doi: 10.1126/science.7123260.

DOI:10.1126/science.7123260
PMID:7123260
Abstract

Intracellular recordings were made from outer hair cells in the third turn of the guinea pig cochlea, and the electrical characteristics of the cells were compared to those of inner hair cells, supporting cells, and extracellular spaces from the same recording region. Outer hair cells have higher membrane potentials than do inner hair cells, but they produce smaller a-c receptor potentials. The frequency response characteristics of both types of hair cells are probably not significantly different. In the frequency region where tuning is optimal, both cell types produce depolarizing d-c receptor potentials, but outer hair cells also generate hyperpolarizing responses at low frequencies.

摘要

在豚鼠耳蜗第三圈的外毛细胞上进行细胞内记录,并将这些细胞的电特性与来自同一记录区域的内毛细胞、支持细胞和细胞外间隙的电特性进行比较。外毛细胞的膜电位比内毛细胞高,但它们产生的交流受体电位较小。两种类型毛细胞的频率响应特性可能没有显著差异。在调谐最佳的频率区域,两种类型的细胞都会产生去极化的直流受体电位,但外毛细胞在低频时也会产生超极化反应。

相似文献

1
Intracellular recordings from cochlear outer hair cells.来自耳蜗外毛细胞的细胞内记录。
Science. 1982 Nov 5;218(4572):582-4. doi: 10.1126/science.7123260.
2
The response of hair cells in the basal turn of the guinea-pig cochlea to tones.豚鼠耳蜗基底转毛细胞对纯音的反应。
J Physiol. 1987 Feb;383:551-69. doi: 10.1113/jphysiol.1987.sp016428.
3
The responses of inner and outer hair cells in the basal turn of the guinea-pig cochlea and in the mouse cochlea grown in vitro.豚鼠耳蜗基底转以及体外培养的小鼠耳蜗中内毛细胞和外毛细胞的反应。
Hear Res. 1986;22:199-216. doi: 10.1016/0378-5955(86)90096-1.
4
Low-frequency characteristics of intracellularly recorded receptor potentials in guinea-pig cochlear hair cells.豚鼠耳蜗毛细胞细胞内记录的感受器电位的低频特性
J Physiol. 1983 May;338:179-206. doi: 10.1113/jphysiol.1983.sp014668.
5
Efferent control of cochlear inner hair cell responses in the guinea-pig.豚鼠耳蜗内毛细胞反应的传出控制
J Physiol. 1984 Sep;354:625-46. doi: 10.1113/jphysiol.1984.sp015396.
6
Influence of direct current on dc receptor potentials from cochlear inner hair cells in the guinea pig.直流电对豚鼠耳蜗内毛细胞直流感受器电位的影响。
J Acoust Soc Am. 1985 Jan;77(1):165-75. doi: 10.1121/1.392282.
7
Intracellular recordings from cochlear inner hair cells: effects of stimulation of the crossed olivocochlear efferents.耳蜗内毛细胞的细胞内记录:交叉橄榄耳蜗传出神经刺激的影响
Science. 1983 Oct 7;222(4619):69-72. doi: 10.1126/science.6623058.
8
Neurobiology of cochlear inner and outer hair cells: intracellular recordings.耳蜗内、外毛细胞的神经生物学:细胞内记录
Hear Res. 1986;22:185-98. doi: 10.1016/0378-5955(86)90095-x.
9
The responses of inner hair cells to basilar membrane velocity during low frequency auditory stimulation in the guinea pig cochlea.豚鼠耳蜗低频听觉刺激期间内毛细胞对基底膜速度的反应。
Hear Res. 1980 Jun;2(3-4):439-45. doi: 10.1016/0378-5955(80)90080-5.
10
Intracellular recordings from supporting cells in the guinea-pig cochlea: AC potentials.
J Acoust Soc Am. 1989 Sep;86(3):1013-32. doi: 10.1121/1.398092.

引用本文的文献

1
Chloride binding does not influence prestin motor speed at very high frequencies in the mouse outer hair cell.在小鼠外毛细胞中,氯化物结合在非常高的频率下不会影响prestin的运动速度。
Structure. 2025 Aug 7;33(8):1417-1424.e3. doi: 10.1016/j.str.2025.04.019. Epub 2025 May 21.
2
The summating potential polarity encodes the ear health condition.总和电位极性可编码耳健康状况。
Cell Mol Life Sci. 2023 May 24;80(6):163. doi: 10.1007/s00018-023-04809-5.
3
Objective Detection of Tinnitus Based on Electrophysiology.基于电生理学的耳鸣检测
Brain Sci. 2022 Aug 16;12(8):1086. doi: 10.3390/brainsci12081086.
4
An outer hair cell-powered global hydromechanical mechanism for cochlear amplification.外毛细胞驱动的耳蜗放大整体液力学机制。
Hear Res. 2022 Sep 15;423:108407. doi: 10.1016/j.heares.2021.108407. Epub 2021 Dec 1.
5
The origin of mechanical harmonic distortion within the organ of Corti in living gerbil cochleae.活体沙鼠耳蜗内 Corti 器官中机械谐波失真的起源。
Commun Biol. 2021 Aug 25;4(1):1008. doi: 10.1038/s42003-021-02540-0.
6
Inner hair cell stereocilia are embedded in the tectorial membrane.内耳毛细胞静纤毛嵌入到盖膜中。
Nat Commun. 2021 May 10;12(1):2604. doi: 10.1038/s41467-021-22870-1.
7
Two-tone distortion in reticular lamina vibration of the living cochlea.活体耳蜗网状板振动的双色失真。
Commun Biol. 2020 Jan 21;3(1):35. doi: 10.1038/s42003-020-0762-2.
8
Organ of Corti vibration within the intact gerbil cochlea measured by volumetric optical coherence tomography and vibrometry.应用体光学相干断层扫描和振动测量法测量完整沙鼠耳蜗中的 Corti 器官振动。
J Neurophysiol. 2018 Dec 1;120(6):2847-2857. doi: 10.1152/jn.00702.2017. Epub 2018 Oct 3.
9
Timing of the reticular lamina and basilar membrane vibration in living gerbil cochleae.活体沙鼠耳蜗网状层和基底膜振动的时间。
Elife. 2018 Sep 5;7:e37625. doi: 10.7554/eLife.37625.
10
Inner Ear Connexin Channels: Roles in Development and Maintenance of Cochlear Function.内耳连接蛋白通道:在耳蜗功能发育和维持中的作用。
Cold Spring Harb Perspect Med. 2019 Jul 1;9(7):a033233. doi: 10.1101/cshperspect.a033233.