Further studies on the role of calcium in the depolarization-induced activation of tryptophan hydroxylase. Effect of verapamil, Tetracaine, haloperidol and fluphenazine.
作者信息
Boadle-Biber M C
出版信息
Biochem Pharmacol. 1982 Aug 1;31(15):2495-503. doi: 10.1016/0006-2952(82)90060-0.
PMID:7126261
Abstract
摘要
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Further studies on the role of calcium in the depolarization-induced activation of tryptophan hydroxylase. Effect of verapamil, Tetracaine, haloperidol and fluphenazine.钙在去极化诱导的色氨酸羟化酶激活中的作用的进一步研究。维拉帕米、丁卡因、氟哌啶醇和氟奋乃静的作用
Biochem Pharmacol. 1982 Aug 1;31(15):2495-503. doi: 10.1016/0006-2952(82)90060-0.
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AGN 2979 [3(3-methoxyphenyl)-3-(3-dimethylaminopropyl)-4, 4-dimethylpiperidine-2,6-dione]. An inhibitor of the activation of tryptophan hydroxylase.AGN 2979 [3-(3-甲氧基苯基)-3-(3-二甲基氨基丙基)-4,4-二甲基哌啶-2,6-二酮]。一种色氨酸羟化酶激活抑制剂。
Biochem Pharmacol. 1986 May 1;35(9):1521-6. doi: 10.1016/0006-2952(86)90119-x.
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Involvement of calmodulin-dependent phosphorylation in the activation of brainstem tryptophan hydroxylase induced by depolarization of slices or other treatments that raise intracellular free calcium levels.钙调蛋白依赖性磷酸化参与切片去极化或其他提高细胞内游离钙水平的处理所诱导的脑干色氨酸羟化酶激活过程。
Biochem Pharmacol. 1987 Apr 1;36(7):1174-6. doi: 10.1016/0006-2952(87)90431-x.
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Blockade by haloperidol of the increase in tryptophan hydroxylase activity induced by incubation of slices of brain stem with dibutyryl cyclic AMP.氟哌啶醇对脑干切片与二丁酰环磷腺苷一起孵育所诱导的色氨酸羟化酶活性增加的阻断作用。
Biochem Pharmacol. 1982 Jun 15;31(12):2203-7. doi: 10.1016/0006-2952(82)90519-6.
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Rat brain stem tryptophan hydroxylase: mechanism of activation by calcium.
J Neurochem. 1977 Apr;28(4):811-8. doi: 10.1111/j.1471-4159.1977.tb10632.x.
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Characterization of the Ca2+-induced proteolytic activation of tryptophan hydroxylase from the rat brain stem.大鼠脑干中钙诱导的色氨酸羟化酶蛋白水解激活特性研究
J Neurochem. 1979 Jun;32(6):1837-44. doi: 10.1111/j.1471-4159.1979.tb02298.x.
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Decrease in the activity of tryptophan hydroxylase from slices of rat brain stem incubated in a low calcium or a calcium-free manganese-substituted medium.
Biochem Pharmacol. 1979 Dec 1;28(23):3487-90. doi: 10.1016/0006-2952(79)90093-5.
8
Activation of tryptophan hydroxylase from slices of rat brain stem incubated with agents which promote calcium uptake or intraneuronal release.用促进钙摄取或神经元内释放的试剂孵育大鼠脑干切片，激活色氨酸羟化酶。
Biochem Pharmacol. 1979 Jul 15;28(14):2129-38. doi: 10.1016/0006-2952(79)90194-1.
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Activation of tryptophan hydroxylase from slices of rat brain stem incubates with N6, 02'-dibutyryl adenosine-3':5'-cyclic monophosphate.用N6, 02'-二丁酰腺苷-3':5'-环磷酸酯培养大鼠脑干切片，可激活色氨酸羟化酶。
Biochem Pharmacol. 1980 Feb 15;29(4):669-72. doi: 10.1016/0006-2952(80)90398-6.
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Phospholipid-induced activation of tryptophan hydroxylase from the rat brainstem.磷脂诱导大鼠脑干色氨酸羟化酶的激活。
Biochem Pharmacol. 1978 Mar 15;27(6):915-22. doi: 10.1016/0006-2952(78)90419-7.
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