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肺癌切除术中不同转移水平的淋巴结图谱绘制与可治愈性

Lymph node mapping and curability at various levels of metastasis in resected lung cancer.

作者信息

Naruke T, Suemasu K, Ishikawa S

出版信息

J Thorac Cardiovasc Surg. 1978 Dec;76(6):832-9.

PMID:713589
Abstract

By means of lymph mapping, the prognosis significance of lymph node metastasis in lung cancer was studied in 270 patients who had undergone radical operations--pulmonary resection combined with complete mediastinal lymph node disection, which is used for patients in whom all cancer could thereby be ablated. Mediastinal lymph node metastasis was found in 64 patients, and 12 patients lived 5 years or more (an absolute 5 year survival rate of 18.8 percent). After radical surgery, there was a significant difference between the prognosis for patients who had metastases to the subcrainal lymph nodes as compared to the prognosis for those who did not. The 5 years survival rates were 9.1 percent and 29.0 percent, respectively. On the other hand, prognosis was not significantly affected by involvement or noninvolvement of the superior mediastinal, paratracheal, tracheobronchial, pretracheal, and the subaortic and para-aortic lymph nodes. No significant difference in survival was detected between patients who were given adjuvant therapy and those who were not. Lymph node mapping gives valuable prognostic information.

摘要

通过淋巴绘图,对270例行根治性手术(肺切除联合完整纵隔淋巴结清扫术,适用于所有癌症均可由此切除的患者)的肺癌患者研究了淋巴结转移的预后意义。64例患者发现纵隔淋巴结转移,12例患者存活5年或更长时间(绝对5年生存率为18.8%)。根治性手术后,锁骨下淋巴结转移患者与未发生转移患者的预后存在显著差异。5年生存率分别为9.1%和29.0%。另一方面,上纵隔、气管旁、气管支气管、气管前、主动脉下和主动脉旁淋巴结是否受累对预后无显著影响。接受辅助治疗的患者与未接受辅助治疗的患者之间未检测到生存率的显著差异。淋巴绘图可提供有价值的预后信息。

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