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鸡法氏囊滤泡髓质细胞的形态学和组织化学特征

Morphological and histochemical characterization of the medullary cells in the bursal follicles of the chicken.

作者信息

Naukkarinen A, Sorvari T E

出版信息

Acta Pathol Microbiol Immunol Scand C. 1982 Aug;90(4):193-9. doi: 10.1111/j.1699-0463.1982.tb01438.x.

DOI:10.1111/j.1699-0463.1982.tb01438.x
PMID:7136706
Abstract

Using light and electron-microscopy and enzyme-histochemical methods the cells in the follicular medulla of the chicken bursa of Fabricius were characterized. The following cell types were identified: lymphocytes of both B and T cell series, lymphoblasts, plasma cells, dendritic reticulum cells and histiocytic reticulum cells--the latter being the only cells phagocytosing the tracer substance used (colloidal carbon). The medullary cells observed showed electron-microscope and histochemical characteristics typical of the germinal center cells in mammalian lymphoreticular tissues. Furthermore, a distinct bursal follicular epithelial cell was identified, and so was a medullary epithelial structure resembling Hassall's corpuscle of the thymus. These findings give further support to the idea that the avian bursa has functions of a peripheral lymphoid organ as well as containing T-derived lymphocytes.

摘要

运用光学显微镜、电子显微镜和酶组织化学方法对鸡法氏囊滤泡髓质中的细胞进行了特征描述。鉴定出了以下细胞类型:B细胞和T细胞系列的淋巴细胞、淋巴母细胞、浆细胞、树突状网状细胞和组织细胞网状细胞——后者是唯一吞噬所用示踪物质(胶体碳)的细胞。观察到的髓质细胞呈现出哺乳动物淋巴网状组织生发中心细胞典型的电子显微镜和组织化学特征。此外,还鉴定出了一种独特的法氏囊滤泡上皮细胞,以及一种类似于胸腺哈氏小体的髓质上皮结构。这些发现进一步支持了禽类法氏囊具有外周淋巴器官功能且含有T衍生淋巴细胞这一观点。

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