中脑电刺激后血清前列腺素E水平升高。
Elevation of serum prostaglandin E levels following electrical stimulation of the midbrain.
作者信息
Rosshirt W, Simon R H, Shaskan E G, Siok C, Dore-Duffy P
出版信息
J Neuroimmunol. 1982 Nov;3(3):219-24. doi: 10.1016/0165-5728(82)90024-8.
PMID:7142380
Abstract
Serum prostaglandin E (PGE) levels were measured in rats immediately following electrical stimulation of the mesencephalic periaqueductal gray (PAG) region and the nucleus raphe magnus (NRM) and compared to controls. An additional group received aspirin prior to PAG stimulation. A significant increase in serum PGE levels was found after stimulation of the PAG, but not the NRM. Aspirin inhibited the stimulation-induced increases in PGE.
摘要
在对大鼠中脑导水管周围灰质（PAG）区域和中缝大核（NRM）进行电刺激后，立即测量其血清前列腺素E（PGE）水平，并与对照组进行比较。另一组在PAG刺激前服用阿司匹林。结果发现，刺激PAG后血清PGE水平显著升高，但刺激NRM后未出现这种情况。阿司匹林抑制了刺激诱导的PGE升高。
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