Maherzi M, Guignard J P, Torrado A
Pediatrics. 1978 Oct;62(4):521-3.
The prevalence of neonatal urinary tract infection (UTI) was studied in 1,762 high-risk neonates. Symptomatic bacteriuria was found in 1.9% and asymptomatic bacteriuria in 0.5% of these neonates. Male preponderance was 5:1. Clinical manifestations were extremely variable--vomiting, weight loss, and diarrhea being the prominent symptoms. Bacteremia was associated with UTI in six infants. The organisms identified in the urine obtained by suprapubic aspiration were Escherichia coli, Klebsiella, and Proteus. A mixed infection was found in four patients. Roentgenographic examination of the urinary tract showed abnormalities in 44% of the symptomatic patients. It is conclued that symptomatic high-risk newborn infants should be screened for bacteriuria, and that radiological investigations be preformed in those with proven infection.
对1762例高危新生儿的新生儿尿路感染（UTI）患病率进行了研究。这些新生儿中，有症状菌尿的发生率为1.9%，无症状菌尿的发生率为0.5%。男性患病率是女性的5倍。临床表现差异极大——呕吐、体重减轻和腹泻是主要症状。6例婴儿的菌血症与UTI相关。经耻骨上膀胱穿刺获取的尿液中鉴定出的病原体为大肠杆菌、克雷伯菌和变形杆菌。4例患者存在混合感染。对尿路进行的X线检查显示，44%有症状的患者存在异常。得出的结论是，应对有症状的高危新生儿进行菌尿筛查，对已证实感染的新生儿进行放射学检查。
