Baron R L, Levitt R G, Sagel S S, White M J, Roper C L, Marbarger J P
Radiology. 1982 Dec;145(3):727-32. doi: 10.1148/radiology.145.3.7146404.
Preoperative determination of the extent of bronchogenic carcinoma at presentation was assessed by CT using a 4th generation scanner with a 3-second scan time in 98 patients whose disease was later surgically staged. Prospective CT interpretations correctly staged 33 of 35 (94%) resectable lesions, and disease in 41 of 45 (91%) patients who had lesions that were not resectable for cure. No definite opinion was rendered on the scans of the remaining 18 patients. Retrospectively analysis using slightly modified criteria resulted in a correct prediction of resectability in 28 of 30 (93%) patients (scans showed a normal mediastinum with no lymph node larger than 1 cm in diameter), and nonresectability for cure in 34 of 34 (100%) patients (scans showed either direct extension of the primary neoplasm into the mediastinum or mediastinal lymph-node enlargement greater than 2 cm in diameter). However, scans of 34 of 98 (35%) patients showed inconclusive findings (mediastinal lymph-nodes with 1-cm to 2-cm diameters, neoplasms abutting but not definitely invading the mediastinum, pleural or pericardial thickening, or additional noncalcified nodules).
对98例后来接受手术分期的患者，使用扫描时间为3秒的第四代扫描仪进行CT检查，以评估就诊时支气管源性癌的术前范围。前瞻性CT判读正确分期了35例可切除病变中的33例（94%），以及45例病变无法根治性切除的患者中的41例（91%）。对其余18例患者的扫描未给出明确意见。使用略有修改的标准进行回顾性分析，结果正确预测了30例患者中28例（93%）的可切除性（扫描显示纵隔正常，无直径大于1 cm的淋巴结），以及34例患者中34例（100%）无法根治性切除（扫描显示原发性肿瘤直接延伸至纵隔或纵隔淋巴结肿大直径大于2 cm）。然而，98例患者中有34例（35%）的扫描结果不明确（纵隔淋巴结直径为1 cm至2 cm，肿瘤紧邻但未明确侵犯纵隔，胸膜或心包增厚，或有其他非钙化结节）。
