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[唾液酸(对25年所获结果的简要综述)]

[Sialic acids (brief review of the results obtained in 25 years)].

作者信息

Cabezas J A

出版信息

Rev Esp Fisiol. 1982;38 Suppl:29-35.

PMID:7146586
Abstract

The main results obtained by the author and collaborators in 25 years' work about the type of sialic acid determined in some materials from the animal kingdom are summarized, with the respective references to the original papers and the indication of the reviews in which they have generally been quoted. The high number of publications on sialic acids from the time of their discovery reflects the increasing interest on these acids in areas such as their chemical composition (16 different sialic acids are now recognized), their distribution in Nature (a not yet well explained topic), their metabolism (which shows differences between bacteria and animal cells) and their biological roles, mainly as a part of glycoproteins and gangliosides (as receptors, markers of the cytoplasmic membrane, viscosity agents of the glycoproteins, life regulators of some substances, etc.).

摘要

作者及其合作者在25年工作中,对动物王国某些材料中所确定的唾液酸类型取得的主要成果进行了总结,并分别列出了原始论文的参考文献以及通常引用这些成果的综述。自唾液酸被发现以来,关于它们的大量出版物反映出在多个领域对这些酸的兴趣日益浓厚,这些领域包括它们的化学组成(目前已识别出16种不同的唾液酸)、在自然界中的分布(一个尚未得到充分解释的课题)、新陈代谢(细菌和动物细胞之间存在差异)以及它们的生物学作用,主要作为糖蛋白和神经节苷脂的一部分(如受体、细胞质膜的标记物、糖蛋白的粘性剂、某些物质的生命调节剂等)。

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