Brown I S, Toolis F, Prescott R J
Scott Med J. 1982 Oct;27(4):279-83. doi: 10.1177/003693308202700403.
A ten-year retrospective study has been undertaken on a group of ten haemophiliacs for whom previous haematological and radiological data was available. Radiological and clinical assessment of their knees and elbows (40 joints) have been correlated to the accurate recording of all haemarthroses suffered by these joints. There is a statistically significant association between the number of haemarthroses and the radiological change in the joint, as determined significant association between number of haemarthroses and deterioration in clinical function. Several bleeds can occur in a haemophilic joint without necessarily causing permanent radiological change; this new finding in adults may be due to modern therapy.
对一组十名血友病患者进行了一项为期十年的回顾性研究，这些患者之前有血液学和放射学数据。对他们的膝盖和肘部（40个关节）进行了放射学和临床评估，并与这些关节所遭受的所有关节积血的准确记录相关联。关节积血的数量与关节的放射学变化之间存在统计学上的显著关联，关节积血的数量与临床功能恶化之间也存在显著关联。血友病关节可能会发生多次出血，但不一定会导致永久性的放射学变化；成人中的这一新发现可能归因于现代治疗方法。
