氟烷试验对氟烷敏感猪以及用β受体阻滞剂（普萘洛尔）进行术前用药的猪的心脏参数、OCT活性、酸碱平衡和血液电解质的影响。
The influence of the halothane test on heart parameters, OCT-activity, acid-base balance and blood electrolytes in halothane-sensitive pigs and in pigs premedicated with a beta-blocker (propranolol).
作者信息
Schulman A
出版信息
Acta Vet Scand. 1982;23(2):153-60. doi: 10.1186/BF03546801.
The heart and liver functions, blood electrolytes and acid-base balance were studies in halothane-sensitive and nonsensitive pigs. An inhibition of the hyperthermia reaction was attempted by an i.v. injection of propranolol. The pulse rate of sensitive pigs was shown to be elevated already at the beginning of halothane narcosis. No other differences between sensitive and nonsensitive pigs were observed from the electrocardiogram. Ectopic beats and arythmia appeared only in 1 halothane-sensitive pig which died soon after the test. The serum OCT-activity showed no abnormalities. Hyperkalemia and acidosis occurred but the Ga was not elevated in halothane-sensitive animals. The slight elevation in Na was thought to be caused by hemoconcentration. A propranolol injection only delayed but did not inhibit the halothane reaction.
对氟烷敏感和不敏感的猪进行了心脏和肝脏功能、血液电解质及酸碱平衡的研究。通过静脉注射普萘洛尔试图抑制体温过高反应。结果显示，敏感猪在氟烷麻醉开始时脉搏率就已升高。从心电图来看，敏感猪和不敏感猪之间未观察到其他差异。异位搏动和心律失常仅出现在1只氟烷敏感猪身上，该猪在试验后不久死亡。血清OCT活性未显示异常。氟烷敏感动物出现了高钾血症和酸中毒，但Ga未升高。Na的轻微升高被认为是由血液浓缩引起的。注射普萘洛尔仅延迟了氟烷反应，但并未抑制该反应。
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