Laude T A, Shah B R, Lynfield Y
Am J Dis Child. 1982 Dec;136(12):1047-50. doi: 10.1001/archpedi.1982.03970480013002.
Tinea capitis, a disease of children, occurs throughout the United States. We studied 144 clinically diagnosed cases of tinea capitis within a 12-month period. Ninety-six of them had positive cultures; Trichophyton tonsurans grew in 89% and Microsporum organisms in 11%. Ninety-five (99%) of the patients with positive cultures were black, and one (1%) was hispanic. The peak incidence was in the 4-to-5-year age group. Boys and girls were equally affected. Sixty percent of the 96 culture-proved cases were noninflammatory, and 40% were inflammatory (kerions). In four patients, the initial clinical manifestations were severe diffuse seborrhealike scales and crusting of the scalp with minimal alopecia. Mycologic and clinical cure were obtained by a mean of 4.7 weeks of griseofulvin therapy. Neither systemic erythromycin, topical antifungal agents, nor systemic prednisone resulted in earlier eradication. However, prednisone caused the inflammation of the kerions to subside dramatically.
头癣是一种儿童疾病,在美国各地均有发生。我们在12个月内研究了144例临床诊断为头癣的病例。其中96例培养结果呈阳性;89%培养出断发毛癣菌,11%培养出小孢子菌属真菌。培养结果呈阳性的患者中95例(99%)为黑人,1例(1%)为西班牙裔。发病高峰年龄在4至5岁组。男孩和女孩受影响程度相同。96例培养确诊病例中,60%为非炎症性,40%为炎症性(脓癣)。4例患者最初的临床表现为严重弥漫性脂溢性皮炎样鳞屑和头皮结痂,脱发轻微。通过平均4.7周的灰黄霉素治疗实现了真菌学和临床治愈。全身用红霉素、外用抗真菌药或全身用泼尼松均未使根除时间提前。然而,泼尼松使脓癣的炎症显著消退。