曲帕拉醇的真菌转化
Fungal transformations of triparanol.
作者信息
Warner S A, Sovocool G W, Domnas A J
出版信息
Appl Environ Microbiol. 1982 Dec;44(6):1471-5. doi: 10.1128/aem.44.6.1471-1475.1982.
Abstract
Fungal transformations of triparanol, a hypercholesterolemic drug, were studied in Lagenidium giganteum and Lagenidium callinectes. The products were identified by combined gas chromatography-mass spectrometry. Two metabolites were observed from each organism; only one of the metabolites was found in both organisms.
摘要
在巨大拉格孢菌和美人虾拉格孢菌中研究了降血脂药物三苯乙醇的真菌转化。产物通过气相色谱 - 质谱联用进行鉴定。从每种生物体中观察到两种代谢物；两种生物体中仅有一种代谢物相同。
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本文引用的文献
1
THE CROSS-LINKS IN RESILIN IDENTIFIED AS DITYROSINE AND TRITYROSINE.在弹性蛋白中鉴定出的交联物为二酪氨酸和三酪氨酸。
Biochim Biophys Acta. 1964 Oct 9;93:213-5. doi: 10.1016/0304-4165(64)90289-2.
2
3
Conversion of beta sitosterol to cholesterol blocked in an insect by hypocholesterolemic agents.在昆虫体内，β-谷甾醇向胆固醇的转化被降胆固醇药物阻断。
Science. 1967 Jun 23;156(3782):1637-8. doi: 10.1126/science.156.3782.1637.
4
Effects of triparanol and AY-9944 upon sterol biosynthesis in Chorella.三苯乙醇和AY-9944对小球藻中甾醇生物合成的影响。
Lipids. 1974 Aug;9(8):567-74. doi: 10.1007/BF02532506.
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