Neville W E
Int Surg. 1982 Jul-Sep;67(3):229-34.
Fifty-four patients with tracheal stenosis due to benign stricture and malignancy underwent airway reconstruction with a molded Silicone prosthesis (Neville Prosthesis). In 40 patients, the trachea was reconstructed with a straight prosthesis; of these 29 had a postintubation stricture and 11 a malignancy. In the former group, there was one early death from erosion of the innominate artery and five late deaths from a variety of causes. The postoperative complications were related to granulomas at the anastomotic site in four patients and were due to the use of non-absorbable suture material. Subglottic granulomas occurred in two patients and were successfully treated with fulguration. The lesion was resected and the trachea reconstructed with the prosthesis in eight individuals, five of whom are alive, one to six years postoperatively. Of the three patients, in whom the prosthesis served as an intraluminal stent, one who received irradiation is alive three years after operation. In 14 patients, in whom a carinal resection was performed for malignancy, five individuals are alive, from one to eleven years after surgery. There were four suture line granulomas in the entire group. All of the deaths were attributable to residual or disseminated cancer.
54例因良性狭窄和恶性肿瘤导致气管狭窄的患者接受了硅胶模制假体(内维尔假体)气道重建术。40例患者采用直形假体重建气管;其中29例为插管后狭窄,11例为恶性肿瘤。在前一组中,有1例因无名动脉侵蚀早期死亡,5例因各种原因晚期死亡。术后并发症与4例患者吻合口处肉芽肿有关,原因是使用了不可吸收缝合材料。2例患者发生声门下肉芽肿,经电灼成功治疗。8例患者病变切除后用假体重建气管,其中5例术后1至6年存活。在3例将假体用作腔内支架的患者中,1例接受放疗的患者术后3年存活。14例因恶性肿瘤行隆突切除的患者中,5例术后1至11年存活。全组有4例缝线处肉芽肿。所有死亡均归因于残留或播散性癌症。