人类恶性黑色素瘤手术或手术加免疫化疗后淋巴细胞玫瑰花结形成能力的变化。
Changes in the rosette forming capacity of lymphocytes after surgery or surgery and immunochemotherapy of malignant melanoma in man.
作者信息
Hadjikirova M, Boeva M, Ikonopisov R
出版信息
Biomed Pharmacother. 1982;36(5):257-9.
The E-rosette forming capacity of lymphocytes was measured in 39 melanoma patients, performing the test at 4 degrees C and at 20 degrees C, prior to treatment, following surgery, and in 11 patients was carried out at three points: before and after surgery as well as after immunochemotherapy with DTIC and BCG. The results have shown a marked depression in E-rosettes at 4 degrees C and at 20 degrees C, whereas more expressed inhibition was registered at 4 degrees C. Following surgical removal there were no significant changes in the E-rosettes. After immunochemotherapy an increase of the E-rosettes was observed.
在39例黑色素瘤患者中检测了淋巴细胞的E花环形成能力，分别在4℃和20℃下进行检测，检测时间点包括治疗前、手术后，并且在11例患者中于三个时间点进行检测：手术前后以及用达卡巴嗪（DTIC）和卡介苗（BCG）进行免疫化疗后。结果显示，在4℃和20℃时E花环均显著降低，而在4℃时抑制作用更明显。手术切除后，E花环无显著变化。免疫化疗后，观察到E花环增加。
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