Holm I, Thulin L, Samnegård H, Efendic S, Tydén G
Acta Physiol Scand. 1978 Oct;104(2):241-3. doi: 10.1111/j.1748-1716.1978.tb06274.x.
Somatostatin, 0.2-1.0 microgram . kg-1 . min-1, was administered i.v. in 5 anesthetized dogs. Following 9-min infusions, hepatic bile output was found to decrease by approximately 50% after a latency of 6 min. The mode of action suggests that somatostatin inhibits hormone-induced bile output.
对5只麻醉犬静脉注射生长抑素,剂量为0.2 - 1.0微克·千克⁻¹·分钟⁻¹。在输注9分钟后,发现肝胆汁分泌量在6分钟的潜伏期后减少了约50%。其作用方式表明生长抑素抑制激素诱导的胆汁分泌。