Trippenbach T, Gaultier C, Cooper L
Can J Physiol Pharmacol. 1982 Oct;60(10):1241-6. doi: 10.1139/y82-181.
Effects of chest compressions on the pattern of breathing were studied in pentobarbital anaesthetized 9- to 11-day-old kittens before and after vagotomy. The chest was compressed by means of a micrometer at three levels (T1-4, T6-8, T9-11). In intact and vagotomized kittens, the group mean values of inspiratory time (tI), expiratory (tE) time, peak amplitude of the integrated phrenic activity (PHR) and its rate of rise (PHR/tI) during compressions were not different from those of the control breaths. On the other hand, in intact kittens during chest compressions variability of all the measured variables significantly increased. In the vagotomized kittens, variability of parameters other than inspiratory time was unaffected. Nevertheless we cannot exclude contribution of extravagal receptors in control of tE. The tE effects could be masked by the increased variability of the control value in vagotomized kittens. The effects of chest compression on the integrated phrenic activity were mostly dependent on the intact vagal feedback.
在戊巴比妥麻醉的9至11日龄小猫迷走神经切断前后，研究了胸部按压对呼吸模式的影响。通过千分尺在三个水平（T1 - 4、T6 - 8、T9 - 11）对胸部进行按压。在完整和迷走神经切断的小猫中，按压期间吸气时间（tI）、呼气时间（tE）、膈神经活动积分的峰值幅度（PHR）及其上升速率（PHR/tI）的组均值与对照呼吸时的值没有差异。另一方面，在完整小猫的胸部按压过程中，所有测量变量的变异性显著增加。在迷走神经切断的小猫中，除吸气时间外的参数变异性未受影响。然而，我们不能排除迷走神经外受体在控制呼气时间方面的作用。在迷走神经切断的小猫中，对照值变异性的增加可能掩盖了呼气时间的影响。胸部按压对膈神经活动积分的影响主要取决于完整的迷走神经反馈。
