Lata A, Satsangi R K, Srivastava V K, Bhargava K P
Pol J Pharmacol Pharm. 1982;34(4):217-22.
Seventeen new 1-(2'-methyl-6'-methoxyquinoline-4'-yl-amino)-2-methyl-4-arylideneimidazol-5-ones have been synthesized by the condensation between the respective azlactones (prepared by the well known Erlenmeyer azlactone synthesis) and 2-methyl-4 hydrazino-6-methoxy-quinolines. The compounds have been found to possess anticonvulsant activity against maximal electroshock seizures and chemoshock induced seizures and the analgesic activity. Some qualitative structure activity relationship has been established.