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视交叉上核、次级同步刺激与昼夜节律的中枢神经控制

Suprachiasmatic nucleus, secondary synchronizing stimuli and the central neural control of circadian rhythms.

作者信息

Moore R Y

出版信息

Brain Res. 1980 Feb 3;183(1):13-28. doi: 10.1016/0006-8993(80)90116-x.

DOI:10.1016/0006-8993(80)90116-x
PMID:7188873
Abstract

The introduction of a secondary synchronizing stimulus, deprivation of water for 22 h each day, with water available during the morning only, to intact adult female rats produces a burst of activity and drinking behavior during and around the time water is available. Normal circadian rhythms in activity and drinking behavior persist through the deprivation period, however, and the morning burst of activity and drinking behavior ceases with the cessation of deprivation schedule. These data indicate that the induced rhythm in activity and drinking behavior is a diurnal, not a circadian rhythm. This view is supported by the fact that a free-running circadian rhythm in activity and drinking behavior persists through a separate period of introduction of the water deprivation schedule even though a diurnal rhythm is once again induced. Suprachiasmatic nucleus ablation abolishes circadian rhythms in activity, drinking and learned behavior, but does not alter the deprivation schedule-induced rhythms.

摘要

对成年雌性大鼠施加二次同步刺激,即每天仅在早晨供应水,其余时间禁水22小时,这会使大鼠在供水期间及前后出现一阵活动和饮水行为。然而,在禁水期间,活动和饮水行为的正常昼夜节律依然存在,并且随着禁水计划的停止,早晨的活动和饮水行为爆发也随之停止。这些数据表明,诱导产生的活动和饮水行为节律是昼夜节律,而非昼夜节律。这一观点得到了以下事实的支持:即使再次诱导出昼夜节律,在单独引入禁水计划的期间,活动和饮水行为的自由运行昼夜节律依然存在。视交叉上核切除会消除活动、饮水和学习行为中的昼夜节律,但不会改变禁水计划诱导的节律。

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引用本文的文献

1
Circadian rhythms and their mechanisms.昼夜节律及其机制。
Experientia. 1986 Jan 15;42(1):1-13. doi: 10.1007/BF01975875.