遗传性躁郁症中的细胞膜异常。

Cell membrane anomaly in genetically determined manic-depressive illness.

作者信息

Verbanck P M, Mendlewicz J

出版信息

Neuropsychobiology. 1981;7(4):185-7. doi: 10.1159/000117849.

PMID:7196512

Abstract

A group of 25 pairs of monozygotic twins has been investigated for twin concordance in relation to affective illness and lithium erythrocyte/plasma ratios. Lithium ratios are significantly greater in twins concordant for affective illness as compared to discordant twins, suggesting the presence of a membrane anomaly as a possible vulnerability factor in subjects genetically predisposed to affective illness.

摘要

对一组25对同卵双胞胎进行了调查，以研究情感性疾病与锂红细胞/血浆比率的双胞胎一致性。与不一致的双胞胎相比，情感性疾病一致的双胞胎的锂比率显著更高，这表明膜异常的存在可能是遗传易患情感性疾病的个体中的一个潜在易感性因素。