Müller H, Börner U, Stoyanov M, Hempelmann G
Anaesthesist. 1980 Dec;29(12):656-7.
Epidural injection of small doses of opiates causes a reduction of pain in the lower parts of the body. The use of epidural opiate-analgesia for surgical anesthesia, combined with controlled ventilation (oxygen-nitrous oxide), was investigated in 170 patients undergoing surgery, especially long lasting gynaecological operations. Haemodynamic monitoring demonstrated a constant cardiovascular situation, underlining the sufficiency of analgesia. Blood gas analyses for one hour after the operation revealed no signs of respiratory depression. The epidural opiate-analgesia outlasted the intraoperative period, covering even the postoperative phase.
硬膜外注射小剂量阿片类药物可减轻身体下部的疼痛。我们对170例接受手术尤其是长时间妇科手术的患者,研究了硬膜外阿片类镇痛联合控制通气(氧气-氧化亚氮)用于手术麻醉的情况。血流动力学监测显示心血管状况稳定,突出了镇痛效果的充分性。术后一小时的血气分析未显示呼吸抑制迹象。硬膜外阿片类镇痛作用持续至术后期,甚至覆盖术后阶段。